Louisville's Upset Bid Against Ole Miss | Louisville Football News

Louisville’s got a big chance to shock the college football world this Sunday night in Nashville, taking on top-ranked Ole Miss as six-and-a-half-point underdogs. To pull off the upset, they’ll need flawless execution: lean on their elite running backs Isaac and Keyjaun Brown, who averaged nearly nine and seven yards per carry last year — targeting Ole Miss’s vulnerable run defense. Their own defense, ranked top-25 against both run and pass, must shut down Ole Miss’s offense while forcing minimal turnovers. With a veteran roster and smart play-calling, Louisville can turn this into a statement win — if they avoid self-inflicted mistakes and stay disciplined. Listen in comfort:Get a discount on a Soli Pillow: http://solipillow.com/discount/dnn. Advertise on DNN:[email protected] This is an automated, high-level news summary based on public reporting.Report issues to [email protected]. View sources & latest updates:https://sources.thednn.ai/fdf52c178b73afae