Low Metabolism and NAD+ Deficiency Implicated in Wasting Syndrome

Muscle wasting in cancer and chronic illness is driven by a breakdown in cellular energy production, not just poor appetite or inflammation Low levels of NAD+, the molecule that powers your cells' mitochondria, cause muscles to weaken and shrink even when calorie intake is sufficient Researchers found that restoring NAD+ with niacin (vitamin B3) helps rebuild muscle mass, improve strength, and stabilize energy metabolism — even during chemotherapy Seed oils high in linoleic acid interfere with how your cells make energy and promote chronic inflammation, while replacing them with stable fats like grass fed butter or ghee supports recovery Simple strategies such as taking niacinamide, eating nutrient-dense whole foods, reducing stress, and getting regular sunlight help recharge your metabolism and rebuild strength from the inside out