Lung cancer in never-smokers: What physicians should know episode artwork

EPISODE · Apr 14, 2026 · 31 MIN

Lung cancer in never-smokers: What physicians should know

from UCI Health Physician Huddle · host UCI Health

In this episode of Physician Huddle by UCI Health, thoracic surgeon Hari B. Keshava, MD, joins the show to discuss the rising incidence of lung cancer in never-smokers, persistent gaps in lung cancer screening, and the growing importance of coordinated follow-up for incidental lung nodules.Keshava also explains how advances in minimally invasive and robotic thoracic surgery, along with targeted therapies and immunotherapy, are reshaping treatment pathways for patients with lung cancer. He also shares his unusual path to medicine, from electrical engineering to thoracic surgery, and reflects on how a personal, family experience with serious lung disease continues to shape the way he cares for patients and their loved ones.Topics discussed: Why lung cancer screening rates have improved, but remain far below where they should beCommon physician and patient barriers to low-dose CT screeningHow to talk with patients about smoking history without judgmentWhat to do when a lung nodule is found incidentallyHow the UCI Health lung nodule clinic helps streamline follow-up and next stepsThe rising incidence of lung cancer in never-smokers, particularly in certain patient populationsQuestions surrounding genetics, driver mutations, and environmental exposureHow robotic and minimally invasive thoracic surgery is improving recoveryWhy targeted therapies and immunotherapy are changing surgical decision-makingKeshava’s path from electrical engineering to thoracic surgeryHow personal experience shapes empathy, expectation-setting, and patient communicationWhat makes thoracic surgery and multidisciplinary cancer care at UCI Health distinctiveConnect with UCI Health physicians online at clinicalconnection.ucihealth.org, on LinkedIn @UCI Health Physicians, on Instagram @ucihealthphysicians, or at @uciphysicians on X. Refer a patient at referralportal.ucihealth.org and learn more about ongoing clinical trials at ucihealth.org/clinical-trials.

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In this episode of Physician Huddle by UCI Health, thoracic surgeon Hari B. Keshava, MD, joins the show to discuss the rising incidence of lung cancer in never-smokers, persistent gaps in lung cancer screening, and the growing importance of coordinated follow-up for incidental lung nodules. Keshava also explains how advances in minimally invasive and robotic thoracic surgery, along with targeted therapies and immunotherapy, are reshaping treatment pathways for patients with lung cancer. He a...

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