Lupus Nephritis: Diagnosis, Classification, Treatment, and The Role of The Pediatrician

Lupus Nephritis: Diagnosis, Classification, Treatment and the Role of the Pediatrician FACULTY: Ruby Patel, MD, is a clinical assistant professor in the division of pediatric nephrology at Stanford University. Rajdeep Pooni, MD, is a clinical assistant professor in the division of pediatric allergy, immunology and rheumatology at Stanford University.   OVERVIEW: Drs. Ruby Patel and Rajdeep Pooni present Grand Rounds using a 12-year-old’s case to illustrate pediatric systemic lupus erythematosus and class IV lupus nephritis, covering presentation, biopsy findings, and pathology. The talk explains diagnostic criteria and typical lab features.   They summarize current management including 2024 ACR guidance on induction therapies (steroids, mycophenolate, cyclophosphamide, and biologics), monitoring for complications and medication side effects, vaccination precautions for immunocompromised patients, and the pediatrician’s role in long-term coordination of care.   OVERALL LEARNING OBJECTIVE: Increased awareness and education for pediatric providers DISCLOSURE TO LEARNERS: Speakers: Ruby Patel, MD and Rajdeep Pooni, MD have no financial relationships with ineligible companies to disclose.   The Pediatrics Now Podcast Planning Committee members: Steven Seidner, MD, and Holly Wayment have no financial relationships with ineligible companies to disclose.   The University of Texas at San Antonio and Steven Seidner, MD course director and content reviewer for the activity, have reviewed all financial disclosure information for all speakers, facilitators, and planning committee members; and determined and resolved all conflicts of interests. CONTINUING MEDICAL EDUCATION STATEMENTS: The University of Texas at San Antonio is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The University of Texas at San Antonio designates this live activity up to a maximum of 1.00 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Successful completion of this CME activity, which includes participation in the activity, with individual assessments of the participant and feedback to the participant, enables the participant to earn 1.00 MOC point in the American Board of Pediatrics’ (ABP) Maintenance of Certification (MOC) program. It is the CME activity provider’s responsibility to submit participant completion information to ACCME for the purpose of granting ABP MOC credit. CERTIFICATE OF ATTENDANCE: Healthcare professionals will receive a certificate of attendance and are asked to consult with their licensing board for information on applicability and acceptance. Credit may be obtained upon successful completion of the activity’s evaluation. RELEASE DATE: 10/17/2025 EXPIRATION DATE: 8/31/2028