Making OnabotulinumtoxinA Injections Less Painful episode artwork

EPISODE · Jul 17, 2026 · 0 MIN

Making OnabotulinumtoxinA Injections Less Painful

from Migraine Minute News Update

Ever wonder if there was a way to make OnabotulinumtoxinA injections less painful? New research suggests using this treatment before injections may help. Molly O'Brien explains in this Migraine Minute news update. Read the study: https://bit.ly/4wRHAFh   Script: For many people with chronic migraine, onabotulinumtoxinA, also known as Botox, is an effective treatment, but it can come with injection pain and post-treatment headache. New research shows there may be an option to help ease that pain. A study published in HEADACHE, found that adults who used a REN, or Remote Electrical Neuromodulation device, felt less pain during injections. The study also found that only 15 percent of those who used the REN device reported post-treatment headache, compared with 55 percent of those who used the fake device. The REN is sold under brand name Nerivio. It's a wearable, drug-free device that delivers electrical pulses to the arm, triggering the body's natural pain relief process. Researchers say these results show Remote Electrical Neuromodulation could be a safe and easy way to make injection treatment sessions more comfortable.

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Making OnabotulinumtoxinA Injections Less Painful

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