Mark Cuban: Disrupting the business of healthcare, part 1 episode artwork

EPISODE · May 13, 2026 · 17 MIN

Mark Cuban: Disrupting the business of healthcare, part 1

from 20-Minute Health Talk · host Northwell Health

In the first episode of this two-part discussion, host Chethan Sathya, MD, sits down with entrepreneur Mark Cuban for a candid look at why Cuban has set his sights on fixing the economics of healthcare. Cuban shares how the “power of broke” shaped his risk mindset, why curiosity beats bravado, and how democratized knowledge and AI are lowering the barrier to entrepreneurship. He unpacks the origin and mission of his new pharmacy business, Cost Plus Drugs, which is all about radical price transparency, straightforward markups, and passing savings to patients. He also discusses his new pushes into mobile pharmaceutical manufacturing and how to apply his Cost Plus Drugs lessons to surgical procedure savings.  Northwell is New York State’s largest healthcare provider and private employer, with 28 hospitals, 890 outpatient facilities and more than 16,600 affiliated physicians. We’re making breakthroughs in medicine at the Feinstein Institutes for Medical Research. We're training the next generation of medical professionals at the visionary Donald and Barbara Zucker School of Medicine at Hofstra/Northwell and the Hofstra Northwell School of Nursing and Physician Assistant Studies. Get the latest news and insights from our experts in the Northwell Newsroom: Press releases Insights Podcasts Publications Interested in a career at Northwell Health? Visit our career site and explore our many opportunities. Watch episodes of 20-Minute Health Talk on YouTube.  For information on our more than 100 medical specialties, visit Northwell.edu and follow us @NorthwellHealth on Facebook, Instagram, X and LinkedIn.

Episode metadata supplied by the publisher feed · Published May 13, 2026

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20-Minute Health Talk host Chethan Sathya, MD, sits down with entrepreneur Mark Cuban for a candid look at why Cuban has set his sights on fixing the economics of healthcare.

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Mark Cuban: Disrupting the business of healthcare, part 1

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