EPISODE · May 13, 2026 · 17 MIN
Mark Cuban: Disrupting the business of healthcare, part 2
from 20-Minute Health Talk · host Northwell Health
In the second part of this conversation between 20-Minute Health Talk host Chethan Sathya, MD, and Mark Cuban, they discuss the twin forces reshaping healthcare: AI and price transparency. He argues that large language models can curb online health misinformation and even augment day-to-day clinical decisions. Cuban dives into policy, praising recent moves to rein in Medicare Advantage overpayments and explaining the drivers of branded drug costs in the U.S. He then unveils Cost Plus Wellness, a push to “open-source” direct contracts between self-insured employers and providers to reduce administrative waste and improve outcomes. Along the way, he makes the case that healthcare is surprisingly easy to disrupt when you understand costs and align incentives. Northwell is New York State’s largest healthcare provider and private employer, with 28 hospitals, 890 outpatient facilities and more than 16,600 affiliated physicians. We’re making breakthroughs in medicine at the Feinstein Institutes for Medical Research. We're training the next generation of medical professionals at the visionary Donald and Barbara Zucker School of Medicine at Hofstra/Northwell and the Hofstra Northwell School of Nursing and Physician Assistant Studies. Get the latest news and insights from our experts in the Northwell Newsroom: Press releases Insights Podcasts Publications Interested in a career at Northwell Health? Visit our career site and explore our many opportunities. Watch episodes of 20-Minute Health Talk on YouTube. For information on our more than 100 medical specialties, visit Northwell.edu and follow us @NorthwellHealth on Facebook, Instagram, X and LinkedIn.
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Mark Cuban tackles the twin forces reshaping healthcare: AI and price transparency. He also argues that large language models can curb online health misinformation and even augment day-to-day clinical decisions.
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Mark Cuban: Disrupting the business of healthcare, part 2
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