Mark Siegel: The Craft of Teaching Doctors

Howie and Harlan are joined by Mark Siegel, director of Yale's internal medicine residency program, to discuss his approach to mentoring young physicians and building a medical community grounded in purpose and compassion. Harlan examines a breakthrough targeted therapy that could reshape the treatment of pancreatic cancer and other hard-to-treat cancers; Howie tracks the Ebola outbreak in the Democratic Republic of the Congo and argues that policy decisions are hampering the global response. Show notes: A Cancer Breakthrough Pancreatic cancer: Symptoms and causes "Daraxonrasib or Chemotherapy in Previously Treated Metastatic Pancreatic Cancer" "Multi-Selective RAS(ON) Inhibitor Nearly Doubles Survival Time in People With Metastatic Pancreatic Cancer" "KRAS mutation: from undruggable to druggable in cancer" Mark Siegel Mark Siegel: Program Director Notes Mark Siegel on Substack Academic medicine Signaling system Mark Siegel: "What I've Learned in 63 Years" Yale School of Medicine: Residency & Fellowship Programs Mark Siegel: "A Sudden Loss Of Vision"  Health & Veritas Episode 224: Nicholas Christakis: The Science of Human Connection Ebola WHO: Bundibugyo virus disease outbreak, Democratic Republic of the Congo WHO: Ebola, The Democratic Republic of the Congo, 2026   WHO: Alert and Response "'We are catching up'—WHO chief on DR Congo's Ebola fight"  "Uganda Closes Border With Congo as Ebola Fears Rise" "Kenyan Court Deals New Blow to Plans for U.S. Ebola Unit" In the Yale School of Management's MBA for Executives program, you'll get a full MBA education in 22 months while applying new skills to your organization in real time. Yale's Executive Master of Public Health offers a rigorous public health education for working professionals, with the flexibility of evening online classes alongside three on-campus trainings. Email Howie and Harlan comments or questions.