Markets Brace for ISM Data as Ethereum and Solana Set Stage for DeFi Reboot

Bitcoin trades at $91,222 as markets await Monday's critical ISM Manufacturing PMI report that could trigger significant repricing. Ethereum breaks above $3,100 with surging open interest while Solana prepares for the Alpenglow upgrade. Memecoins rally sharply with PEPE up 17% and Dogecoin gaining 4%. Regulatory clarity drives institutional adoption as former CFTC Acting Chair Caroline Pham declares 2026 the year institutions go all-in on crypto. XRP gains regulatory backing for RLUSD stablecoin under bank-level oversight. Security concerns remain as hundreds of MetaMask wallets were drained in phishing attacks. Plus, geopolitical volatility from Venezuela military action briefly impacts markets before recovery.