Mast Cell Activation and Histamine Intolerance with Dr. Kelly McCann episode artwork

EPISODE · Mar 9, 2026 · 45 MIN

Mast Cell Activation and Histamine Intolerance with Dr. Kelly McCann

from Healing Powers Podcast · host Laura Powers

In this episode of the Healing Powers Podcast, host Laura Michelle Powers speaks with medical doctor and functional medicine expert Dr. Kelly McCann about mast cell activation syndrome (MCAS), histamine intolerance, and the growing number of people experiencing unexplained chronic symptoms. Although mast cell activation was only first described in medical literature in 2007, research suggests that up to one in five people may be affected.Dr. McCann explains how mast cells—an important part of the immune system—can become overly reactive due to environmental toxins, mold exposure, infections, stress, and trauma. When this happens, it can trigger widespread inflammation throughout the body and lead to symptoms such as allergies, brain fog, digestive issues, insomnia, migraines, anxiety, and fatigue. Laura also shares her own experiences with mold exposure and sensitivities, highlighting how many people struggle to get answers through conventional testing.Learn more about Dr. Kelly McCann at thespringcenter.com As Dr. Kelly referenced, you can find more information and locate mold-aware professionals through the International Society for Environmentally Acquired Illness (ISEAI): https://iseai.org/Kelly K. McCann, MD, MPH is a triple board-certified physician in Internal Medicine, Pediatrics, and Integrative Medicine, with additional certifications in Functional Medicine and Medical Acupuncture. She is the founder of The Spring Center in Costa Mesa, California, where she specializes in complex chronic illness, including Mast Cell Activation Syndrome, mold and mycotoxin illness, Lyme disease, and environmentally acquired conditions.Dr. McCann has hosted multiple international summits on MCAS and allergy-related illness and serves on the boards of the American Academy of Environmental Medicine and was a founding Board member of the International Society for Environmentally Acquired Illness. A graduate of Tulane University School of Medicine and one of only 35 physicians worldwide to complete the residential fellowship at the University of Arizona’s Center for Integrative Medicine, she also holds a Master’s in Spiritual Psychology.Her work is now evolving into what she calls The Unforgetting Project: a new healing paradigm that bridges functional medicine with spiritual psychology, inviting patients to experience symptoms not as failures, but as meaningful messages guiding them back to wholeness.Laura is a Celebrity Psychic who has been featured by Buzzfeed, The Weakest Link, Beast Games, NBC, ABC, CBS, FOX, the CW, Motherboard by Vice Magazine and the #1” Ron Burgundy Podcast” with Will Ferrell. Laura Powers is a clairvoyant, psychic medium, writer, actress, producer, writer, and speaker who helps other receive guidance and communicate with loved ones. Laura travels nationally and internationally for clients, events, television appearances, and speaking engagements. She is also the author of 7 books on the psychic realm and 1 book on podcasting. Laura also works as a psychic, entertainer, and creative entrepreneur.For more information about Laura and her work, you can go to her website www.healingpowers.net or find her on X @thatlaurapowers, on Facebook at @realhealingpowers and @mllelaura, and on Instagram, TikTok and Insight Timer @laurapowers44.

In this episode of the Healing Powers Podcast, host Laura Michelle Powers speaks with medical doctor and functional medicine expert Dr. Kelly McCann about mast cell activation syndrome (MCAS), histamine intolerance, and the growing number of people experiencing unexplained chronic symptoms. Although mast cell activation was only first described in medical literature in 2007, research suggests that up to one in five people may be affected.Dr. McCann explains how mast cells—an important part of the immune system—can become overly reactive due to environmental toxins, mold exposure, infections, stress, and trauma. When this happens, it can trigger widespread inflammation throughout the body and lead to symptoms such as allergies, brain fog, digestive issues, insomnia, migraines, anxiety, and fatigue. Laura also shares her own experiences with mold exposure and sensitivities, highlighting how many people struggle to get answers through conventional testing.Learn more about Dr. Kelly McCann at thespringcenter.com As Dr. Kelly referenced, you can find more information and locate mold-aware professionals through the International Society for Environmentally Acquired Illness (ISEAI): https://iseai.org/Kelly K. McCann, MD, MPH is a triple board-certified physician in Internal Medicine, Pediatrics, and Integrative Medicine, with additional certifications in Functional Medicine and Medical Acupuncture. She is the founder of The Spring Center in Costa Mesa, California, where she specializes in complex chronic illness, including Mast Cell Activation Syndrome, mold and mycotoxin illness, Lyme disease, and environmentally acquired conditions.Dr. McCann has hosted multiple international summits on MCAS and allergy-related illness and serves on the boards of the American Academy of Environmental Medicine and was a founding Board member of the International Society for Environmentally Acquired Illness. A graduate of Tulane University School of Medicine and one of only 35 physicians worldwide to complete the residential fellowship at the University of Arizona’s Center for Integrative Medicine, she also holds a Master’s in Spiritual Psychology.Her work is now evolving into what she calls The Unforgetting Project: a new healing paradigm that bridges functional medicine with spiritual psychology, inviting patients to experience symptoms not as failures, but as meaningful messages guiding them back to wholeness.Laura is a Celebrity Psychic who has been featured by Buzzfeed, The Weakest Link, Beast Games, NBC, ABC, CBS, FOX, the CW, Motherboard by Vice Magazine and the #1” Ron Burgundy Podcast” with Will Ferrell. Laura Powers is a clairvoyant, psychic medium, writer, actress, producer, writer, and speaker who helps other receive guidance and communicate with loved ones. Laura travels nationally and internationally for clients, events, television appearances, and speaking engagements. She is also the author of 7 books on the psychic realm and 1 book on podcasting. Laura also works as a psychic, entertainer, and creative entrepreneur.For more information about Laura and her work, you can go to her website www.healingpowers.net or find her on X @thatlaurapowers, on Facebook at @realhealingpowers and @mllelaura, and on Instagram, TikTok and Insight Timer @laurapowers44.

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This episode is 45 minutes long.

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This episode was published on March 9, 2026.

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In this episode of the Healing Powers Podcast, host Laura Michelle Powers speaks with medical doctor and functional medicine expert Dr. Kelly McCann about mast cell activation syndrome (MCAS), histamine intolerance, and the growing number of people...

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