MASTERCLASS: What CREST-2 Means for Carotid Disease Management

In this episode of the Neurocritical Care Society Podcast Masterclass series, hosts Stephan Mayer, MD, FCCM, FNCS, and Jon Rosenberg, MD, are joined by Seemant Chaturvedi, MD, professor of neurology and director of the Stroke Division at the University of Maryland, for an in-depth discussion on carotid disease, stroke prevention and the role of revascularization in clinical practice. The episode explores the historical impact of NASCET, key findings from the CREST-2 trial and the role of intensive medical management for patients with asymptomatic carotid stenosis. Dr. Chaturvedi also shares practical guidance for neurointensivists caring for patients with symptomatic carotid disease, including intervention timing, risk stratification and emerging diagnostic tools such as MRI plaque imaging and TCD microemboli monitoring. The views expressed on the NCS Podcast are solely those of the hosts and guests and do not necessarily reflect the opinions or official positions of the Neurocritical Care Society.