Mathias Foo (River systems and biochemical control) episode artwork

EPISODE · Jun 1, 2025 · 1H 10M

Mathias Foo (River systems and biochemical control)

from Coffee and Control · host Lucy Hodgins

In this episode I interview Dr Mathias Foo about his fascinating research on controlling river systems, implementing control systems using DNA, and gene network rewiring. Basically applying control to a bunch of different systems that you weren’t expecting. You can find the transcript for this episode at: https://docs.google.com/document/d/1cWRFK20bWm64k7MCghI82eJ3-FjTt3hK0VEpQ-VE0Og/edit?usp=sharing Connect with me and with the podcast!LinkedIn: https://www.linkedin.com/in/lucy-hodgins-733a30175/X: https://x.com/coffee_ctrl_podBluesky: https://bsky.app/profile/coffee-and-control.bsky.socialInstagram: https://www.instagram.com/coffee_and_control_podcast/  ReferencesDr Mathias Foo: https://warwick.ac.uk/fac/sci/eng/people/mathias_foo/ PhDPhD thesis: https://scholar.google.com/citations?view_op=view_citation&hl=en&user=H5eLRq4AAAAJ&cstart=20&pagesize=80&sortby=pubdate&citation_for_view=H5eLRq4AAAAJ:2osOgNQ5qMECNadia Bedjaoui: https://www.linkedin.com/in/nadia-bedjaoui-39862110/Observers for leak detection in irrigation channels: https://www.sciencedirect.com/science/article/abs/pii/S0967066110001498MPC using reverse engineering paper: https://ieeexplore.ieee.org/abstract/document/6114363Maciejowski MPC book: https://www.amazon.com/Predictive-Control-Constraints-Jan-Maciejowski/dp/0201398230Maciejowski inverse optimal control paper: https://www.sciencedirect.com/science/article/pii/S1474667015366180 DNA strand displacement reactionsOishi and Klavins paper: https://www.dna.caltech.edu/courses/cs191/paperscs191/Oishi2011linear.pdfDNA amplifiers: https://www.science.org/doi/10.1126/science.1148532DNA Logic gates: https://www.science.org/doi/10.1126/science.1132493DNA Detectors: https://www.dna.caltech.edu/Papers/Nucleation_DNA10.pdfPID control using DSD reactions: https://ieeexplore.ieee.org/document/8721529Nuno Paulino: https://scholar.google.com/citations?user=FKL-xegAAAAJ&hl=en&oi=aoDNA programmable gate arrays: https://www.nature.com/articles/s41586-023-06484-9Theoretical DNA feedback paper: https://www.mdpi.com/2306-5354/10/4/466DNA stability paper: https://www.sciencedirect.com/science/article/pii/S0005109820303010SSV DNA robustness paper: https://ieeexplore.ieee.org/stamp/stamp.jsp?arnumber=8619072Gomez-Uribe covalent modification cycle paper: https://pubmed.ncbi.nlm.nih.gov/18159939/Quasi sliding-model controller paper: https://ieeexplore.ieee.org/document/7833853Design based on covalent modification cycle: https://link.springer.com/article/10.1186/s13036-016-0036-1PI-degradation controllers: https://warwick.ac.uk/fac/sci/eng/staff/dgb/077972431.pdf Gene regulatory networksVoit S-system paper: https://doi.org/10.1042/bse0450029Modelling and control using S-system models: https://ieeexplore.ieee.org/abstract/document/8254368Extended S-system model for restoring circadian cycles: https://www.nature.com/articles/s41540-022-00216-xUri Alon gene regulation paper: https://www.nature.com/articles/nrg2102Network re-wiring paper: https://pubs.acs.org/doi/full/10.1021/acssynbio.8b00037Reverse-engineering Hill-type models paper: https://royalsocietypublishing.org/doi/abs/10.1098/rsif.2024.08112009 Cell optimisation paper: https://www.sciencedirect.com/science/article/pii/S0092867409007120Briat antithetic integral control paper: https://www.cell.com/fulltext/S2405-4712(16)00005-3Professor Declan Bates: https://warwick.ac.uk/fac/sci/eng/staff/dgb/Steve Brunton: https://www.youtube.com/@EigensteveControl bootcamp series: https://www.youtube.com/watch?v=Pi7l8mMjYVE&list=PLMrJAkhIeNNR20Mz-VpzgfQs5zrYi085mPhysics-informed machine learning series: https://www.youtube.com/watch?v=JoFW2uSd3Uo&list=PLMrJAkhIeNNQ0BaKuBKY43k4xMo6NSbBaProbability and statistics series: https://www.youtube.com/watch?v=sQqniayndb4&list=PLMrJAkhIeNNR3sNYvfgiKgcStwuPSts9V

Episode metadata supplied by the publisher feed · Published Jun 1, 2025

In this episode I interview Dr Mathias Foo about his fascinating research on controlling river systems, implementing control systems using DNA, and gene network rewiring. Basically applying control to a bunch of different systems that you weren’t expecting. You can find the transcript for this episode at: https://docs.google.com/document/d/1cWRFK20bWm64k7MCghI82eJ3-FjTt3hK0VEpQ-VE0Og/edit?usp=sharing Connect with me and with the podcast!LinkedIn: https://www.linkedin.com/in/lucy-hodgins-733a30175/X: https://x.com/coffee_ctrl_podBluesky: https://bsky.app/profile/coffee-and-control.bsky.socialInstagram: https://www.instagram.com/coffee_and_control_podcast/  ReferencesDr Mathias Foo: https://warwick.ac.uk/fac/sci/eng/people/mathias_foo/ PhDPhD thesis: https://scholar.google.com/citations?view_op=view_citation&hl=en&user=H5eLRq4AAAAJ&cstart=20&pagesize=80&sortby=pubdate&citation_for_view=H5eLRq4AAAAJ:2osOgNQ5qMECNadia Bedjaoui: https://www.linkedin.com/in/nadia-bedjaoui-39862110/Observers for leak detection in irrigation channels: https://www.sciencedirect.com/science/article/abs/pii/S0967066110001498MPC using reverse engineering paper: https://ieeexplore.ieee.org/abstract/document/6114363Maciejowski MPC book: https://www.amazon.com/Predictive-Control-Constraints-Jan-Maciejowski/dp/0201398230Maciejowski inverse optimal control paper: https://www.sciencedirect.com/science/article/pii/S1474667015366180 DNA strand displacement reactionsOishi and Klavins paper: https://www.dna.caltech.edu/courses/cs191/paperscs191/Oishi2011linear.pdfDNA amplifiers: https://www.science.org/doi/10.1126/science.1148532DNA Logic gates: https://www.science.org/doi/10.1126/science.1132493DNA Detectors: https://www.dna.caltech.edu/Papers/Nucleation_DNA10.pdfPID control using DSD reactions: https://ieeexplore.ieee.org/document/8721529Nuno Paulino: https://scholar.google.com/citations?user=FKL-xegAAAAJ&hl=en&oi=aoDNA programmable gate arrays: https://www.nature.com/articles/s41586-023-06484-9Theoretical DNA feedback paper: https://www.mdpi.com/2306-5354/10/4/466DNA stability paper: https://www.sciencedirect.com/science/article/pii/S0005109820303010SSV DNA robustness paper: https://ieeexplore.ieee.org/stamp/stamp.jsp?arnumber=8619072Gomez-Uribe covalent modification cycle paper: https://pubmed.ncbi.nlm.nih.gov/18159939/Quasi sliding-model controller paper: https://ieeexplore.ieee.org/document/7833853Design based on covalent modification cycle: https://link.springer.com/article/10.1186/s13036-016-0036-1PI-degradation controllers: https://warwick.ac.uk/fac/sci/eng/staff/dgb/077972431.pdf Gene regulatory networksVoit S-system paper: https://doi.org/10.1042/bse0450029Modelling and control using S-system models: https://ieeexplore.ieee.org/abstract/document/8254368Extended S-system model for restoring circadian cycles: https://www.nature.com/articles/s41540-022-00216-xUri Alon gene regulation paper: https://www.nature.com/articles/nrg2102Network re-wiring paper: https://pubs.acs.org/doi/full/10.1021/acssynbio.8b00037Reverse-engineering Hill-type models paper: https://royalsocietypublishing.org/doi/abs/10.1098/rsif.2024.08112009 Cell optimisation paper: https://www.sciencedirect.com/science/article/pii/S0092867409007120Briat antithetic integral control paper: https://www.cell.com/fulltext/S2405-4712(16)00005-3Professor Declan Bates: https://warwick.ac.uk/fac/sci/eng/staff/dgb/Steve Brunton: https://www.youtube.com/@EigensteveControl bootcamp series: https://www.youtube.com/watch?v=Pi7l8mMjYVE&list=PLMrJAkhIeNNR20Mz-VpzgfQs5zrYi085mPhysics-informed machine learning series: https://www.youtube.com/watch?v=JoFW2uSd3Uo&list=PLMrJAkhIeNNQ0BaKuBKY43k4xMo6NSbBaProbability and statistics series: https://www.youtube.com/watch?v=sQqniayndb4&list=PLMrJAkhIeNNR3sNYvfgiKgcStwuPSts9V

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In this episode I interview Dr Mathias Foo about his fascinating research on controlling river systems, implementing control systems using DNA, and gene network rewiring. Basically applying control to a bunch of different systems that you weren’t...

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