MDM2 Gene Amplification: William Sukov, M.D.

William Sukov, M.D., provides an overview of the MDM2 gene amplification assay — a test that looks for amplification of the MDM2 gene region on chromosome 12q. He reviews when this test should be ordered, how it compares to other test options, and how its

Episode 35 of the Answers from the Lab podcast, hosted by Mayo Clinic Laboratories, titled "MDM2 Gene Amplification: William Sukov, M.D." was published on October 20, 2020 and runs 6 minutes.

October 20, 2020 ·6m · Answers from the Lab

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Summary

William Sukov, M.D., provides an overview of the MDM2 gene amplification assay — a test that looks for amplification of the MDM2 gene region on chromosome 12q. He reviews when this test should be ordered, how it compares to other test options, and how its results can affect patient care.

Episode Description

Speaker 1: (01:20)
Today we want to talk about the MDM2 gene amplification assay. Can you give us a little bit of an overview of that test?

Speaker 1: (02:16)
Is there a certain subset of patients that should have this testing, and when should it be performed on those patients?

Speaker 1: (02:50)
So for those patients then, are there any other alternative test options that are available for them, or how else might these patients be diagnosed, and how does this specific task compare with the other options out there?

Speaker 1: (03:59)
It sounds like this test is going to be used primarily for a diagnosis in this specific case. Then how does that impact patient care?

Speaker 1: (04:50)
Can you explain this in a way that a patient would understand why this test would be done?

Resources
MDM2 (12q15) Amplification, Well-Differentiated Liposarcoma/Atypical Lipomatous Tumor, FISH, Tissue

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