Medication Review: Guselkumab IV vs SC Formulation

Thank you to Johnson & Johnson for their support on this Medication Review Video Module. In this quick educational video, Angelina Collins, NP, from the University of California San Diego Inflammatory Bowel Disease Center, discusses an important question in Crohn’s disease treatment. This overview breaks down the key findings from the GALAXI and GRAVITI clinical trials in a clear, practical way, helping healthcare providers better understand the effectiveness and safety of both treatment approaches for patients with moderate to severe Crohn’s disease. Angelina explains the differences between IV and subcutaneous induction dosing, maintenance treatment options, and how these choices can support shared decision-making between providers and patients. Whether patients are new to advanced therapies or have previous biologic experience, this discussion highlights how both induction options may provide strong results without compromising safety. This video is designed for gastroenterology APPs, nurse practitioners, physician assistants, gastroenterologists, and healthcare professionals looking for practical insights into Crohn’s disease management and evolving IBD treatment strategies. For more GI and hepatology education, visit the GHAPP Digital Hub and the GHAPP ACE app.