Medicinal Chemistry: A Molecular and Biochemical Approach

Provides an overview of drug design principles, pharmacology, and molecular properties of various therapeutic agents. It systematically covers fundamental concepts like the general molecular principles of drug design, including how molecules are conceptualized as active fragments (pharmacophores, toxicophores), and the role of bioisosteres in optimization. Significant sections are dedicated to the structure and properties of drug receptors (such as ion channels and G-proteins) and different neurotransmitters and hormones (including cholinergic, adrenergic, steroid, and opioid systems), discussing their mechanisms of action and related drugs. Finally, the text explores drug targets at the cellular and macromolecular level, focusing on areas like anticancer agents, antibiotics for exogenous pathogens, and the pharmaceutical relevance of various biological macromolecules and inorganic substances.You can listen and download our episodes for free on more than 10 different platforms:https://linktr.ee/pharmacy_simpleProduced by:https://www.podcaistudio.com/