Memory and the Brain (S2E24)

In this week’s episode, we explore one of the most crucial aspects of the human experience; memory. We start off with a phenomenon Lauren finds particularly interesting: Highly Superior Autobiographical Memory, in which individuals can recall specific, extremely detailed aspects of their daily lives spanning years and even decades in the past. From there we discuss How do we store memories? What different facets and types of memory are there? What is going on with Alzheimer’s and Dementia. We also discuss some historical figures in memory research (e.g., H.M.), eye witness testimonies, place cells, and erasing memories. References: Howard, M. W., & Eichenbaum, H. (2013). The hippocampus, time, and memory across scales. Journal of Experimental Psychology. General, 142(4), 1211-1230. doi:10.1037/a0033621 Jeneson, A., & Squire, L. R. (2012;2011;). Working memory, long-term memory, and medial temporal lobe function. Learning & Memory (Cold Spring Harbor, N.Y.), 19(1), 15-25. doi:10.1101/lm.024018.111 LePort, A. K., Mattfeld, A. T., Dickinson-Anson, H., Fallon, J. H., Stark, C. E., Kruggel, F., . . . McGaugh, J. L. (2012). Behavioral and neuroanatomical investigation of Highly Superior Autobiographical Memory (HSAM). Neurobiology of Learning and Memory, 98(1), 78-92. doi:https://doi.org/10.1016/j.nlm.2012.05.002 Nowak, C., & Nowak, C. (2017, November 10). Only 60 People in the World Have This Insanely Powerful Memory. Retrieved from https://www.rd.com/health/conditions/highly-superior-autobiographical memory/ Palombo, D. J., Alain, C., Soderlund, H., Khuu, W., & Levine, B. (2015). Severely deficient autobiographical memory (SDAM) in healthy adults: A new mnemonic syndrome. Neuropsychologia, 72, 105-118. doi:https://doi.org/10.1016/j.neuropsychologia.2015.04.012 Simons, J. S., & Spiers, H. J. (2003). Prefrontal and medial temporal lobe interactions in long-term memory. Nature Reviews Neuroscience, 4(8), 637-648. doi:10.1038/nrn1178 Other Resources: 25, R. D. (n.d.). The 5 Types of Memory Everyone Has and Why They Matter. Retrieved from https://www.rd.com/health/wellness/memory-types/ ALifeJournal. (2016, December 05). Retrieved February 21, 2019, from https://www.youtube.com/watch?v=Gnel7xQTFvI The sections of the Medial Temporal Lobe are what is responsible for memory. This demonstrates the components as well as their function.: https://en.wikipedia.org/wiki/Temporal_lobe#Structure: Gaitan, R. (2016, April 16). Retrieved February 21, 2019, from https://www.youtube.com/watch?v=1fV3jafglNo: This video discusses Neurons and their role in forming memories. It discusses the Prefrontal Cortex, where memories and associations are formed. For example, he uses Diet Coke as his example and discusses how your sense of taste and memory works so that when you drink Diet Coke, you remember the taste associated and can identify. Frontotemporal Dementia. Retrieved from https://www.ucsfhealth.org/conditions/frontotemporal_dementia/: This page discusses a condition called Frontotemporal Dementia. It impacts about as many people as Domentia does, accept, it is experienced by those who are a little younger than those who experience Domentia The age range identified is between 40 and 60 years old. ANTEROGRADE AMNESIA. Retrieved from http://www.human memory.net/disorders_anterograde.html H.M.: https://en.wikipedia.org/wiki/Henry_Molaison Clive Wearing: https://en.wikipedia.org/wiki/Clive_Wearing Place Cells & Temporal Cells: https://www.ted.com/talks/neil_burgess_how_your_brain_tells_you_where_you_are/transcript?language=en Replacing memories: https://www.youtube.com/watch?v=zRuUQiIgyj4