Mendelian Randomisation in Cardiovascular Research - Assumptions, Pitfalls & Practice

Send us Fan MailHost Pablo Perel and co-host Prof. Raul Santos talk with Dr Jiao Luo about Mendelian randomisation (MR) in cardiovascular research, what it is, core assumptions (relevance, independence, no horizontal pleiotropy), common pitfalls (weak instruments, population mismatch, non-linearity), and how to read MR papers. The episode references:Unraveling the Causal Links Between Immune Cells, Lipids, and Cardiovascular Diseases: Insights from Mendelian Randomization  and  Mendelian Randomisation: Concepts, Opportunities, Challenges, and Future Directions.