Metformin, Men, and Birth Defects

A recent study evaluated the role of metformin in causing birth defects, but when the men are prescribed metformin. This obstetrics study evaluates the role of the partner in risk for birth defects. Does the study change practice? Listen as host Geoff Wall discusses how pregnancy involves both partners. The GameChanger Emerging data suggest that male metformin use during sperm development may increase the risk of birth defects, specifically among baby boys. Show Segments 00:00 - Introduction 01:23 - Metformin Use in Males & Birth Defects 12:29 - The GameChanger 17:29 - Discussing Risk with Patients 19:39 - Closing Remarks Host Geoff Wall, PharmD., BCPS, FCCP, CGP Professor of Pharmacy Practice, Drake University Internal Medicine/Critical Care, UnityPoint Health All relevant financial relationships have been mitigated. References and Resources Preconception Antidiabetic Drugs in Men and Birth Defects in Offspring: A Nationwide Cohort Study Redeem your CPE or CME CPE (Pharmacists) CME (Physicians) Get a membership & earn CE for GameChangers Podcast episodes (30 mins/episode) Pharmacists: Get a membership Prescribers: Get a membership CE Information Learning Objectives 1. Describe the design for a population health study using a national database 2. Discuss what type of birth defects were associated with male metformin use in the study 0.05 CEU/0.5 Hr UAN: 0107-0000-22-213-H01-P Initial release date: 05/16/2022 Expiration date: 05/16/2023 Additional CPE and CME details can be found here. Follow CEimpact on Social Media: LinkedIn Instagram