Midlife Is a Lipid Neighborhood: Cholesterol, Insulin & The “Got Plaque, Get a CAC” Wake-Up Call (Season 2 Premiere w/ Josh Wageman, PhD, DPT) episode artwork

EPISODE · Dec 24, 2025 · 1H 2M

Midlife Is a Lipid Neighborhood: Cholesterol, Insulin & The “Got Plaque, Get a CAC” Wake-Up Call (Season 2 Premiere w/ Josh Wageman, PhD, DPT)

from Second Opinion · host Rosemarie Beltz

Season 2 starts here. And we’re coming in hot—with clarity, comedy, and one of the most misunderstood topics in modern medicine: cholesterol.In this Season Two premiere, I’m joined by Josh Wageman, PhD, DPT—lipid specialist, former Ivy League athlete, and yes… a youth pastor—who has a gift for making complex science feel human (and finally understandable). His core message? Cholesterol isn’t just “good vs. bad.” It’s a system. And midlife is when the system starts telling the truth.We break down why your labs may not “add up,” why insulin is the quiet driver behind so many chronic diseases, and why the goal isn’t obsessing over one number—it’s protecting your heart, your brain, and your future.If you’ve ever stared at your lipid panel and thought, “Wait… what does this actually mean for me?” — this episode is your reset.In this episode, we cover:Why cholesterol stays confusing (even for proactive, educated patients)Josh’s “home security system + lipid neighborhood” framework for preventionThe connection between insulin resistance and cardiovascular risk (even with “normal” glucose)Why fasting insulin can reveal what standard labs miss“Got plaque, get a CAC”: why a coronary artery calcium score can change the entire conversationHDL, LDL, triglycerides, ApoB, Lp(a): what matters, what’s misleading, and what needs contextThe statin conversation—without fear, drama, or tribalismWhy alcohol can raise HDL (and why that doesn’t always mean “better”)How to think like a high performer: movement, prevention, and the long game of longevityMy Season Two intention: My goal for my life is complete longevity—living my most optimal life. And this season, I’m bringing you with me: my curiosity, my questions, and the conversations I wish every mid-lifer had access to sooner.Because getting a second opinion isn’t just smart medicine. It’s smart living.Connect and  follow the show:Website and  listener submissions: RosemarieB.com Send your questions, guest suggestions, and story ideas—I read every one. If this episode supported you, please follow the show and leave a quick review. It helps more mid-lifers find better answers.Signed with love and a dash of Midlife Magic,  ✨ Rosemarie Book mentioned:The Home Security System and the Lipid Neighborhood by Josh Wageman (available on Amazon and Audible)The Home Security System and the Lipid Neighborhood: Un-Complicating Cholesterol and Cardiovascular Disease: Wageman, Josh: 9798992169218: Amazon.com: Books 🔗 Follow & Subscribe to never miss an episode. If you love the show, leave a review—it helps others get a second opinion!💡 Have a topic you’d love for us to cover? Reach out at www.rosemarieb.com.

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Midlife Is a Lipid Neighborhood: Cholesterol, Insulin & The “Got Plaque, Get a CAC” Wake-Up Call (Season 2 Premiere w/ Josh Wageman, PhD, DPT)

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