Migraines: Are They More Than a Headache?

 In this episode, we explore the intricate world of migraines, a condition affecting one in eight people globally. Discover the five phases of a migraine—prodrome, aura, headache, postdrome, and interictal—and how each contributes to the overall experience. We delve into the role of the hypothalamus, the brain's stability center, in triggering migraines and the various symptoms it causes. Learn about potential triggers, the pain pathways involved, and effective relief methods. Tune in to understand migraines better and find ways to manage this disabling condition. Participate in clinical research!www.ENCOREdocs.comShare with a friend. Rate, Review, and Subscribe to the ENCORE Research Group podcast to be notified when new episodes are released.Follow us on Social Media:FacebookInstagramTwitterLinkedInTiktokFor more great content, including discussions by physicians and clinical research experts, check out the MedEvidence podcast. www.MedEvidence.comThank you for listening!References:Burstein, R., Noseda, R., & Borsook, D. (2015). Migraine: multiple processes, complex pathophysiology. Journal of Neuroscience, 35(17), 6619-6629. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412887/Kelman, L. (2004). The premonitory symptoms (prodrome): a tertiary care study of 893 migraineurs. Headache: The Journal of Head and Face Pain, 44(9), 865-872. https://doi.org/10.1111/j.1526-4610.2004.04168.xKoren, M. J., Toenjes, S. (May 13, 2024). Two docs talk: Migraines. MedEvidence Podcast. (Podcast). https://medevidence.com/two-docs-talk-migrainesInternational Headache Society. (2019). 1.3 Chronic migraine  https://ichd-3.org/1-migraine/1-3-chronic-migraine/ Accessed 15 Jan 2024.Maniyar, F. H., Sprenger, T., Monteith, T., Schankin, C., & Goadsby, P. J. (2014). Brain activations in the premonitory phase of nitroglycerin-triggered migraine attacks. Brain, 137(1), 232-241. https://academic.oup.com/brain/article/137/1/232/363839May, A., & Burstein, R. (2019). Hypothalamic regulation of headache and migraine. Cephalalgia, 39(13), 1710-1719. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7164212/Saper, C. B., & Lowell, B. B. (2014). The hypothalamus. Current Biology, 24(23), R1111-R1116. https://www.sciencedirect.com/science/article/pii/S0960982214012998Share with a friend. Rate, Review, and Subscribe to MedEvidence! Articles to be notified when new episodes are released.Follow us on Social Media:FacebookInstagramTwitterLinkedInTiktokYoutubeFor more great content, including discussions by physicians and clinical research experts, check out the MedEvidence! Podcast and MedEvidence.comThank you for listening!