Mobility, Metabolism, and Resilience: Translating Geroscience into Function — A Conversation with Steve Kritchevsky episode artwork

EPISODE · Apr 1, 2026 · 44 MIN

Mobility, Metabolism, and Resilience: Translating Geroscience into Function — A Conversation with Steve Kritchevsky

from Decoding Longevity · host Raghav Sehgal

What if aging isn’t defined by disease — but by how much function we preserve over time?In this episode of Decoding Longevity, Raghav Sehgal and Macsue Jacques sit down with Stephen Kritchevsky to explore how mobility, metabolism, and physiological resilience shape the aging process.From walking speed as a powerful integrative biomarker… to why muscle quality may matter more than muscle mass… to what long-term trials like Look AHEAD reveal about bending aging trajectories — this conversation reframes longevity around function, not just lifespan.We also dive into the trade-offs of weight loss in older adults, the connection between brain and physical aging, and what it will take to measure — and truly slow — aging in humans.

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Mobility, Metabolism, and Resilience: Translating Geroscience into Function — A Conversation with Steve Kritchevsky

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