MONKEYPOX & OTHER PLAGUES | Medicine & Health Podcast

A few months ago, Dr. A talked about the smallpox threat, its history, and the likelihood of it happening. Well now we are hearing about "monkeypox": What is it, is it related to smallpox, is there a known treatment and vaccine, what's the disease like, and how dangerous is it? We will dive into these and more related topics!LINKS OF INTEREST: DrA Online YouTube Channel: https://www.youtube.com/channel/UC1FLIaKDzkU5Z0knDYYKyPQ/videos DrA TikTok: https://www.tiktok.com/@dra_online SMALLPOX, ANTHRAX, and BIOTERROR https://youtu.be/rJYxiFcJjNw CDC US Cases 06-01-22 https://www.cdc.gov/poxvirus/monkeypox/response/2022/index.html Dr. Prasad Monkeypox https://youtu.be/vyUkGQBV9LM Dr. Campbell NIH, Wuhan were working on monkeypox https://www.youtube.com/watch?v=4E6cD-VWhQY Actual transmission data on smallpox: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3509329/ FDA Vax approval 2019 https://www.fda.gov/news-events/press-announcements/fda-approves-first-live-non-replicating-vaccine-prevent-smallpox-and-monkeypox MedCram Video heat Rx (Start at 11 min 20 sec) https://youtu.be/6sdvw_0R240 Last Post-COV &Vax Podcast: https://youtu.be/DK6-HbhRdGs Last “COVID and Me” podcasts “Part-1” https://youtu.be/bZsAwz5lBFM & Part-2 https://youtu.be/A46L6OgQrZ0 “Get and Stay Healthy” podcast: https://youtu.be/5uFWq27ZjBo COVID and B vs T cell immunity https://youtu.be/kUrXqptZEXA “You’ve got COVID, Now What?” https://youtu.be/GXxR8MH-6Ig Vitamin D pre-exposure and severity data: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8509048/ Nutrients in COVID: https://dranow.com/nutrients-covid-19/ https://www.cdc.gov/poxvirus/monkeypox/about.html Monkeypox is a rare disease that is caused by infection with monkeypox virus. Monkeypox virus belongs to the Orthopoxvirus genus in the family Poxviridae. The Orthopoxvirus genus also includes variola virus (which causes smallpox), vaccinia virus (used in the smallpox vaccine), and cowpox virus.Monkeypox was first discovered in 1958 when two outbreaks of a pox-like disease occurred in colonies of monkeys kept for research, hence the name ‘monkeypox.’ The first human case of monkeypox was recorded in 1970 in the Democratic Republic of the Congo (DRC) during a period of intensified effort to eliminate smallpox. Since then, monkeypox has been reported in people in several other central and western African countries: Cameroon, Central African Republic, Cote d’Ivoire, Democratic Republic of the Congo, Gabon, Liberia, Nigeria, Republic of the Congo, and Sierra Leone. The majority of infections are in Democratic Republic of the Congo.Monkeypox cases in people have occurred outside of Africa linked to international travel or imported animals, including cases in the United States, as well as Israel, Singapore, and the United Kingdom.The natural reservoir of monkeypox remains unknown. However, African rodents and non-human primates (like monkeys) may harbor the virus and infect people.Clinical Recognition https://www.cdc.gov/poxvirus/monkeypox/clinicians/clinical-recognition.html You can recognize potential monkeypox infection based on the similarity of its clinical course to that of ordinary discrete smallpox.After infection, there is an incubation period which lasts on average 7-14 days. The development of initial symptoms (e.g., fever, malaise, headache, weakness, etc.) marks the beginning of the prodromal period.A feature that distinguishes infection with monkeypox from that of smallpox is the development of swollen lymph nodes (lymphadenopathy). Swelling of the lymph nodes may be generalized (involving many different locations on the body) or localized to several areas (e.g., neck and armpit).Shortly after the prodrome, a rash appears. Lesions typically begin to develop simultaneously and evolve together on any given part of the body. The evolution of lesions progresses through four stages—macular, papular, vesicular, to pustular—before scabbing over and resolving.This process happens over a period of 2-3 weeks. The severity of illness can depend upon the initial health of the individual, the route of exposure, and the strain of the infecting virus (West African vs. Central African virus genetic groups, or clades). West African monkeypox is associated with milder disease, fewer deaths, and limited human-to-human transmission. Human infections with the Central African monkeypox virus clade are typically more severe compared to those with the West African virus clade and have a higher mortality. Person-to-person spread is well-documented for Central African monkeypox virus.