Morbidity and Mortality — The Real Cost of Untreated Obesity episode artwork

EPISODE · Mar 10, 2026 · 6 MIN

Morbidity and Mortality — The Real Cost of Untreated Obesity

from Weight and Metabolism · host Dr Deepti Sharma, MD

This episode is about understanding what's really at stake when obesity goes untreated — not to scare you, but to give you clarity on why this work matters so much.Let me start by explaining two critical medical terms: mortality (death) and morbidity (illness and its impact on quality of life). Think of a hurricane: mortality is how many people it kills, morbidity is how many survive but live with injuries or damaged homes. That's what obesity does to the body.Mortality: Obesity is an independent risk factor for premature death. All-cause mortality increases progressively with higher BMI, especially over 30. In the U.S., obesity contributes to about 300,000 deaths each year. Severe obesity (BMI over 40) can reduce life expectancy by 5 to 20 years.Morbidity: Even before death, obesity burdens every organ system. Cardiovascular disease (the #1 cause of death worldwide), type 2 diabetes, sleep apnea, fatty liver disease, osteoarthritis, chronic pain, infertility, and at least 16 types of cancer — including colorectal, breast, pancreatic, liver, and endometrial cancer. Then there's the psychosocial toll: depression, anxiety, low self-esteem, stigma, and discrimination.And the epidemic is growing. In 2022, 1 in 8 people globally were living with obesity. Adult obesity has doubled since 1990. Adolescent obesity has quadrupled. In the U.S., 42.4% of adults have obesity, and 75% of adults are either overweight or obese.Here's the sobering truth: In the last 40 years, no country in the world has made meaningful progress against obesity. So what are we doing wrong? Where is our understanding and treatment limited?That's my why. As a physician, I see every day how obesity is the common thread behind so many medical conditions. This isn't about vanity. This is about saving lives and improving quality of life. And that's why addressing obesity is imperative — because if we don't, we're not really addressing chronic disease at the root cause level.In the next episode, I'll share how I approach obesity in my clinic and how this model can translate to everyday life.🌐 Learn more at weightandmetabolism.com

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