Mother of Methadone and Fighting Against Today’s Addiction Crisis episode artwork

EPISODE · Dec 1, 2025 · 56 MIN

Mother of Methadone and Fighting Against Today’s Addiction Crisis

from Commonwealth Club of California Podcast · host Commonwealth Club of California

Dr. Melody Glenn was a burned-out emergency physician who had grown to resent the large population of opioid-dependent patients passing through her ER. While working at a methadone clinic, she realized how effective harm reduction treatments could be and set out to discover why they weren’t used more broadly. That’s when she found Dr. Marie Nyswander. In the 1960s, Dr. Nyswander defied the DEA and medical establishment to co-develop methadone maintenance as a treatment for heroin addiction. According to some addiction specialists, its discovery could be considered as monumental as the discovery of penicillin. Yet, it still carries a stigma today. As the United States continues to struggle with opioid and fentanyl use, Dr. Glenn shares Dr. Nyswander’s legacy and important lessons that can be used in dealing with today’s addiction crisis. Dr. Melody Glenn is an author and associate professor of addiction and emergency medicine at the University of Arizona. She graduated with her M.D. from The University of Southern California, completed her emergency medicine residency at Maricopa Medical Center, and earned her EMS fellowship from The University of California, San Francisco. Moderator Margaret Juhae Lee is the author of Starry Field: A Memoir of Lost History. She received a Bunting Fellowship from Harvard University and a Korean Studies Fellowship from the Korean Foundation in support of research for her book. Previously, she was an editor for the Books and the Arts section at The Nation magazine. Commonwealth Club World Affairs of California is a nonprofit public forum; we welcome donations made during registration to support the production of our programming. A Psychology Member-led Forum program. Forums at the Club are organized and run by volunteer programmers who are members of The Commonwealth Club, and they cover a diverse range of topics. Learn more about our Forums. Commonwealth Club World Affairs is a public forum. Any views expressed in our programs are those of the speakers and not of Commonwealth Club World Affairs. OrganizerPatrick O'Reilly  Learn more about your ad choices. Visit megaphone.fm/adchoices

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