MSK: Psoriatic Arthritis: Free MSRA Podcast

⚕️ FREE MSRA PODCAST – Psoriatic Arthritis🎧 A clear, high-yield breakdown of this chronic joint-skin inflammatory condition – perfect for exam prep and real-life clinical scenarios.🧠 Key Learning Points📌 Definition• A chronic inflammatory arthritis associated with psoriasis, affecting both joints and skin.• Can present before or after the onset of psoriasis.📌 Causes & Risk Factors• Genetic predisposition (e.g. HLA-B27 gene)• Family history of PSA• Severe or extensive psoriasis• Nail involvement• Obesity and smoking• Environmental triggers: trauma, infections🧠 Mnemonic: HOPES – HLA-B27, Obesity, Psoriasis, Environmental triggers, Smoking📌 Pathophysiology• Autoimmune attack on joints and entheses• Inflammatory cascade → synovitis, enthesitis, dactylitis• Systemic inflammation may affect eyes (uveitis), cardiovascular system, and more📌 Symptoms• Joint pain, stiffness (esp. morning), and swelling• Dactylitis – “sausage digits”• Enthesitis – heel, Achilles pain• Psoriatic nail changes: pitting, onycholysis• Fatigue🧠 Mnemonic: PAINS – Pain, Achilles enthesitis, Inflammation, Nail changes, Sausage digits📌 Differential Diagnosis• Rheumatoid arthritis (RA)• Gout• Reactive arthritis• Ankylosing spondylitis• Enteropathic arthritis (IBD)• Septic arthritis• Juvenile idiopathic arthritis📌 Diagnosis• Primarily clinical – psoriasis + inflammatory arthritis signs• Inflammatory markers: ↑ ESR/CRP• Rheumatoid factor usually negative• Imaging: X-ray (erosions, new bone), MRI (early sacroiliitis)• HLA-B27 and serum IgA may support diagnosis🧠 Tip: Remember “RF-negative with psoriasis” = Think PSA!📌 Management• Mild disease: – NSAIDs + PPI cover – Intra-articular steroids – Physiotherapy• Moderate/severe disease: – DMARDs (e.g. Methotrexate, Sulfasalazine) – Biologics (e.g. TNF-alpha inhibitors)• Non-pharmacological: – Physio & occupational therapy – Weight loss, smoking cessation – Lifestyle modifications• Surgical options (if severe joint damage): – Joint replacement, synovectomy📌 Complications• Joint destruction and deformity• Functional disability• Uveitis• Increased cardiovascular risk (due to chronic inflammation)• Rare: aortitis, neurological issues📌 Prognosis• Highly variable.• Early diagnosis and aggressive treatment improve outcomes and preserve quality of life.📎 More MSRA Resources for Psoriatic Arthritis📝 Revision Notes:https://www.passthemsra.com/topic/psoriatic-arthritis-revision-notes/🧠 Flashcards:https://www.passthemsra.com/topic/psoriatic-arthritis-flashcards/💬 Accordion Q&A Notes:https://www.passthemsra.com/topic/psoriatic-arthritis-accordion-qa-notes/🚀 Rapid Quiz:https://www.passthemsra.com/topic/psoriatic-arthritis-rapid-quiz/https://www.passthemsra.com/quizzes/psoriatic-arthritis/🎓 Full Course:https://www.passthemsra.com/courses/msk-for-the-msra/Hashtags#MSRA #MSRARevision #MSRATextbook #MSRAQuiz #MSRAQuestionBank #MSRAFlashcards #MSRAQ&ANotes #MSRAAccordions #MultiSpecialityRecruitmentAssessment #MSRAOnlineRevision #MSRARevisionWebsite #PsoriaticArthritis