MTS13 - Joel Sussman - Proteopedia.org and Intrinsically Unstructured Proteins

Joel Sussman, Ph.D. is a professor of structural biology at the Weizmann Institute of Science in Israel. In his research, Dr. Sussman is interested in elucidating the structures and functions of proteins, particularly those involved in the nervous system. He is also the lead scientist behind Proteopedia – a new online protein structure encyclopedia. Scientific endeavors have historically been a one-way street: an investigator or lab makes a discovery, then delivers the good news to the rest of the community via publication. Nowadays, computers and the internet are enabling easier and more seamless means of collaboration and communication. Proteopedia, with which Dr. Sussman is greatly involved, automatically gathers and compiles information from multiple curated sources of information, but its more revolutionary side is the wiki tool, which enables registered users to contribute information themselves. In this interview with Dr. Sussman, I talked with him about his work with acetylcholinesterase and “intrinsically unstructured proteins” and about Proteopedia – how it works and about the possibility of misinformation making its way onto the site. The video extra shows Proteopedia in action. It is narrated by Eran Hodis, the graduate student, who, together with Professors Jaime Prilusky & Joel L. Sussman developed Proteopedia at the Weizmann Institute of Science.