Mutant cells in the esophagus, and protecting farmers from dangerous pesticide exposure

As you age, your cells divide over and over again, leading to minute changes in their genomes. New research reveals that in the lining of the esophagus, mutant cells run rampant, fighting for dominance over normal cells. But they do this without causing any detectable damage or cancer. Host Sarah Crespi talks to Phil Jones, a professor of cancer development at the University of Cambridge in the United Kingdom, about what these genome changes can tell us about aging and cancer, and how some of the mutations might be good for you. Most Western farmers apply their pesticides using drones and machinery, but in less developed countries, organophosphate pesticides are applied by hand, resulting in myriad health issues from direct exposure to these neurotoxic chemicals. Host Meagan Cantwell speaks with Praveen Vemula, a research investigator at the Institute for Stem Cell Biology and Regenerative Medicine in Bengaluru, India, about his latest solution—a cost-effective gel that can be applied to the skin to limit pesticide-related toxicity and mortality. This week’s episode was edited by Podigy. Download a transcript of this episode (PDF) Listen to previous podcasts. About the Science Podcast [Image:Navid Folpour/Flickr; Music: Jeffrey Cook] Learn more about your ad choices. Visit megaphone.fm/adchoices