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脑肠轴下的非药物治疗新技术:低频经颅磁刺激(rTMS)治疗 episode artwork

EPISODE · Aug 24, 2026 · 9 MIN

脑肠轴下的非药物治疗新技术:低频经颅磁刺激(rTMS)治疗

from 消化肝病前沿资讯

本期播客聚焦肠易激综合征腹泻型(IBS-D),解析最新研究发现:内侧前额叶皮层(mPFC)是内脏疼痛调控核心,其神经元异常兴奋通过ACC-mPFC通路及NR2A分子上调引发症状。研究证实低频经颅磁刺激(rTMS)可无创抑制mPFC活性,显著缓解患者疼痛并改善肠道功能,为脑肠轴机制下的非药物治疗提供新方向。 00:06 IBS-D症状与疾病特点 00:42 mPFC是疼痛指挥中心 01:42 ALFF值揭示神经活动异常 02:37 小鼠模型验证疼痛机制 03:33 神经通路抑制缓解疼痛 04:27 NR2A分子机制新发现 05:19 rTMS无创治疗新方案 06:04 rTMS精准作用于mPFC 06:56 临床疗效与随访结果 07:30 研究局限与未来方向 08:11 脑肠轴与个性化医疗 08:55 研究启示与治疗展望 09:38 感谢收听与下期预告

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脑肠轴下的非药物治疗新技术:低频经颅磁刺激(rTMS)治疗

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