Navigating the Role of Leucovorin in Autism Care

Recent FDA actions have brought renewed attention to leucovorin as a potential treatment for managing symptoms associated with autism spectrum disorder. This course explores the clinical distinctions between autism and cerebral folate deficiency, reviews key evidence behind leucovorin use, and outlines counseling considerations relevant to pharmacy practice. You will gain clarity on this complex and evolving topic to better support informed, evidence-based care. HOST Rachel Maynard, PharmD GameChangers Podcast Host and Clinical Editor, CEimpact Lead Editor, Pyrls GUEST Geoff Wall, PharmD, FCCP, BCPS Professor of Pharmacy Practice Iowa Methodist Medical Center Rachel Maynard and Geoff Wall have no relevant financial relationships to disclose. GET CE FOR LISTENING! Stay Compliant. Grow Clinically. Practice with Confidence. Pharmacist CE Subscription: All your CE in one convenient subscription. All episodes, CE, and Practice Resources for the GameChangers Clinical Update is included with your Pharmacist CE Subscription. But wait…there’s even more! What the Subscription Includes: The Pharmacist CE Subscription includes: · Compliance and licensure CE · GameChangers Clinical Updates · Practical continuing education across patient care topics *The subscription does not include microcredentials or certificates, which are available separately for pharmacists seeking specialized service training. Purchase Now! PRACTICE RESOURCE Receive the exclusive Practice Resource to use as a reference guide for this episode by purchasing the Pharmacist CE Subscription. CPE REDEMPTION This course is accredited for continuing pharmacy education! Click the link below that applies to you to take the exam and evaluation to claim credit: If you are already enrolled in this course, click here to redeem your credit. To purchase the Pharmacist CE Subscription and claim your CPE credit, click here or to purchase this course individually, click here. CPE INFORMATION Learning Objectives Upon successful completion of this knowledge-based activity, participants should be able to: 1. Describe current clinical evidence related to the use of leucovorin in autism and cerebral folate deficiency. 2. Identify key counseling considerations for pharmacists discussing leucovorin therapy with patients and caregivers. 0.05 CEU/0.5 Hr UAN: 0107-0000-25-363-H01-P Initial release date: 12/1/2025 Expiration date: 12/1/2026 Additional CPE details can be found here. Follow CEimpact on Social Media: LinkedIn Instagram