NBS #121: The Hidden Connection Between Mold, Lyme, and MCAS episode artwork

EPISODE · Mar 20, 2026 · 1H 6M

NBS #121: The Hidden Connection Between Mold, Lyme, and MCAS

from Never Been Sicker · host Michael Rubino

Send us Fan MailWhat if one of the biggest reasons people stay stuck in chronic illness recovery is mold?In this episode of Never Been Sicker, Michael Rubino sits down with integrative medicine practitioner Michelle McKeon to talk about the overlap between mold exposure, Lyme disease, mast cell activation syndrome (MCAS), long COVID, immune dysregulation, and personalized treatment.Michelle shares why more patients today need customized care, how mold can suppress the immune system and complicate recovery, and why treatment order matters so much for sensitive people. Michael also explains why proper home investigation and remediation are essential if someone wants real, sustainable progress.In this episode, they cover:- Why mold is often a major missing piece in recovery- The connection between mold, Lyme, and MCAS- Why some people flare from supplements and detox protocols- How long COVID and environmental exposure may overlap- Why generalized testing and treatment often miss the full picture- How personalized care can help sensitive patients move forwardIf you’ve been dealing with mold illness, chronic inflammation, Lyme, long COVID, or MCAS, this episode connects many of the dots.Timestamps0:00 Intro0:31 Michelle introduces her background and work2:54 Personalized medicine and personalized remediation4:16 Why some patients need a more customized approach5:16 FMT and gut microbiome support for sensitive patients7:08 Blood cleansing therapies and lingering inflammatory burdens11:28 Michael asks about long COVID and indoor air quality13:10 Toxic bucket theory, mold exposure, and MCAS15:16 Why mold is a major factor for so many chronic illness patients16:58 The problem with poor inspections and bad remediation18:42 Why drainage pathways and sequencing matter in recovery21:18 Michael explains why center-of-room air sampling is flawed24:08 Why thorough remediation matters26:25 Why more patients now understand mold is serious28:13 Michelle shares her own experience with humidity and VOCs30:48 Looking at the body and home holistically31:14 The Lyme and mold connection34:47 Why aggressive treatment can backfire in sensitive patients36:58 Nervous system regulation and trauma in chronic illness37:23 The emotional cost of getting dismissed by doctors38:42 Do you need to treat mold before Lyme?40:38 Mold’s impact on psychiatric symptoms and brain inflammation42:56 Mold, anxiety, depression, and root cause medicine47:00 What MCAS is and why it matters53:24 Michael asks the biggest lie Michelle has uncovered54:25 Michelle says the biggest lie is that mold is not that serious55:58 Michael explains why “mold is everywhere” is misleading1:05:22 Wrap-up and where to find Michelle-----------------------------------------------------------------------------------------------🔵 About Michelle :Michelle McKeon is the owner of The Lyme Specialist, a Licensed Integrative Nutritionist, and Certified Mold Practitioner specializing in tick-borne infections, environmental toxins, gut health, and inflammatory conditions. After overcoming her own severe battle with Lyme disease and co-infections, Michelle went on to earn her master’s degree in Human Nutrition and now helps clients address root causes including mold mycotoxins, infections, genetics, and detox challenges. She is also an author, speaker, and advocate for people navigating complex chronic illness.🔵 Follow her:Website: https://thelymespecialist.comInstagram: https://www.instagram.com/thelymespecialist/-----------------------------------------------------------------------------------------------🔵 My Favorite Cleaning Products: https://www.homecleanse.com/shop/🔵 Remediation FREE Consultation: https://www.homecleanse.com/contact/🔵 The Dust Test: https://www.thedusttest.com

Episode metadata supplied by the publisher feed · Published Mar 20, 2026

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Send us Fan Mail What if one of the biggest reasons people stay stuck in chronic illness recovery is mold? In this episode of Never Been Sicker, Michael Rubino sits down with integrative medicine practitioner Michelle McKeon to talk about the overlap between mold exposure, Lyme disease, mast cell activation syndrome (MCAS), long COVID, immune dysregulation, and personalized treatment. Michelle shares why more patients today need customized care, how mold can suppress the immune system and c...

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NBS #121: The Hidden Connection Between Mold, Lyme, and MCAS

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