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NEJM This Week — December 4, 2025

Podcast of news and medicine from the NEJM.

Episode 22 of the NEJM This Week podcast, hosted by The New England Journal of Medicine, titled "NEJM This Week — December 4, 2025" was published on December 3, 2025 and runs 21 minutes.

December 3, 2025 ·21m · NEJM This Week

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We discuss the latest in medical research and ideas.

This week, we look at new trials on glucocorticoids for pneumonia in Africa, shunting for normal-pressure hydrocephalus, and pegcetacoplan for two rare kidney diseases. We review updated vaccine evidence for Covid-19, RSV, and influenza, and present a case of respiratory decline and muscle weakness. Perspectives explore health care incentives, U.S. global health strategy, and bringing AI-enabled care to rural America.

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