NEJM This Week — March 26, 2026

from NEJM This Week · host The New England Journal of Medicine

This week, we present new clinical trials on immunotherapy for stage III mismatch repair–deficient colon cancer, early surgery for asymptomatic aortic stenosis, an approach to dengue virus suppression, and advances in gene and prime-editing therapies for rare disorders. We also review minipuberty. We follow the case of a 12-year-old girl with altered mental status and persistent hypoglycemia, and we explore Perspectives on corporate influences on health, vaccine communication, antitrust policy, conflicts of interest, and the meaning of the number needed to treat.

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NEJM This Week — March 26, 2026

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This episode is 27 minutes long.

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This episode was published on March 25, 2026.

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