Nerandomilast bei idiopathischer Lungenfibrose: Verlangsamung des Lungenfunktionsverlustes über 52 Wochen

from Study Snacks - Pneumologie · host Thieme Gruppe

Nerandomilast ist ein Inhibitor der Phosphodiesterase 4B mit antifibrotischer und immunmodulatorischer Wirkung und konnte in einer Phase-2-Studie bei idiopathischer Lungenfibrose über 12 Wochen die Lungenfunktion stabilisieren. Richeldi et al. wollten nun im nächsten Schritt mehr über Sicherheit und Wirksamkeit von Nerandomilast über einen längeren Zeitraum erfahren und kommen in ihrer Phase-3-Studie zu einem positiven Fazit. Studie (PubMed): https://pubmed.ncbi.nlm.nih.gov/40387033/ [1] Richeldi L et al. Nerandomilast in Patients with Idiopathic Pulmonary Fibrosis. N Engl J Med 2025. doi: 10.1056/NEJMoa2414108 Zu Risiken und Nebenwirkungen lesen Sie die Packungsbeilage und fragen Sie Ihre Ärztin, Ihren Arzt oder in Ihrer Apotheke. In diesem Audio sind mit Hilfe von künstlicher Intelligenz (KI) oder maschineller Übersetzungstechnologie gesprochene Texte enthalten [elevenlabs.io].

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Nerandomilast bei idiopathischer Lungenfibrose: Verlangsamung des Lungenfunktionsverlustes über 52 Wochen

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