Neurocutaneous Disorders in Pregnancy: Rare but must know for MFMs

This podcast examines the management of neurocutaneous disorders during pregnancy, specifically focusing on conditions like Neurofibromatosis (Types 1 and 2), Tuberous Sclerosis Complex, Sturge-Weber syndrome, and Von Hippel–Lindau syndrome. The podcast highlights that these rare genetic conditions often lead to increased maternal and neonatal morbidity, including hypertensive disorders, seizures, and accelerated tumor growth due to hormonal shifts. To mitigate risks such as preterm labor or neurological deterioration, we advocate for a multidisciplinary care team involving maternal-fetal medicine specialists, neurologists, and anesthesiologists. Preconception counseling, genetic testing, and frequent imaging are emphasized as vital components for optimizing health outcomes. Ultimately, the source provides a clinical framework for obstetricians to navigate the complex physiological interactions between these systemic disorders and the demands of pregnancy.