Neuroinflammation drug discovery in stem cell-derived microglia

In this week’s podcast we explore why Microglia are awesome, why our panellists use induced pluripotent stem cell models and how they feed Genome wide association studies hits and basic science into drug discovery with phenotypic screening. Meet our panellists: Dr Hazel Hall-Roberts, who is a black belt in Wado-Ryu karate and Postdoctoral Research Scientist at the Sir William Dunn School of Pathology & ARUK Oxford Drug Discovery Institute. Dr Emma Mead a Senior Neurobiologist, allotment holder, kitchen creative and Team Leader at the ARUK Oxford Drug Discovery Institute. Maria Kreger Karabova a DPhil student also at Sir William Dunn School of Pathology, University of Oxford. Maria’s claim to fame is that she once overhead-squatted her postdoc supervisor (I am sure a few of us would like to do that). Megan Calvert-O’Hare is hosting the discussion which was recorded over Zoom (so apologies if the sounds quality isn’t up to our usual high standards). You can find out more about our panellists, and their work on our website www.dementiaresearcher.nihr.ac.uk. A transcript of this podcast is also available here https://www.dementiaresearcher.nihr.ac.uk/podcast-neuroinflammation-drug-discovery-in-stem-cell-derived-microglia _____________________________________________________________________ This podcast is brought to you in association with Alzheimer's Research UK and Alzheimer's Society, who we thank for their ongoing support.