Neuroprotective Strategies in Glaucoma: Current Evidence and Future Directions

Glaucoma is often described as a pressure disease, but at its core it's a disease of dying nerve cells. In this episode, Dr. Saikumar Gandapodi joins us to unpack what neuroprotection really means in glaucoma, why lowering eye pressure remains the foundation of care, and where the gaps in that approach open the door for adjunct strategies.We explore the biology of retinal ganglion cell loss, the roles of ocular blood flow, mitochondrial function, oxidative stress, and neurotrophin decline, and what the human evidence actually supports versus what remains hypothesis. Dr. Gandapodi also explains how his integrative framework, Netra Restoration Therapy, is intended to complement conventional treatment rather than replace it.This is a candid, evidence-informed conversation for anyone who wants to understand where glaucoma care is heading and how to think clearly about promise versus proof.