Neurotrophic Keratopathy (NK) Is When the Eye Can’t See What’s Happening

In this week's episode, we take a closer look at Neurotrophic Keratopathy (NK), a rare nerve condition affecting the eye. We explore how the eye works, the risks of developing NK, possible complications of the disease, and what is actually happening within the eye. We also dive into current treatments, including an new investigational class of medications being researched.References: Dua HS, Said DG, Messmer EM, Rolando M, Benitez-del-Castillo JM, Hossain PN, Shortt AJ, Geerling G, Nubile M, Figueiredo FC, Rauz S. Neurotrophic keratopathy. Progress in retinal and eye research. 2018 Sep 1;66:107-31. https://doi.org/10.1016/j.preteyeres.2018.04.003Gipson IK. The ocular surface: the challenge to enable and protect vision: the Friedenwald lecture. Investigative ophthalmology & visual science. 2007 Oct 1;48(10):4391-8. https://doi.org/10.1167/iovs.07-0770Vera-Duarte GR, Jimenez-Collado D, Kahuam-López N, Ramirez-Miranda A, Graue-Hernandez EO, Navas A, Rosenblatt MI. Neurotrophic keratopathy: General features and new therapies. Survey of Ophthalmology. 2024 Sep 1;69(5):789-804. https://www.sciencedirect.com/science/article/pii/S0039625724000420Gurnani B, Feroze KB, Patel BC. Neurotrophic keratitis. InStatPearls [Internet] 2025 Mar 27. StatPearls Publishing. https://www.ncbi.nlm.nih.gov/books/NBK431106/Share with a friend. Rate, Review, and Subscribe to MedEvidence! Articles to be notified when new episodes are released.Follow us on Social Media:FacebookInstagramTwitterLinkedInTiktokYoutubeFor more great content, including discussions by physicians and clinical research experts, check out the MedEvidence! Podcast and MedEvidence.comThank you for listening!