Niners’ Defense and Trenches Under Fire | San Francisco 49ers News

The Niners face a tough Week One test against the Rams as a two-and-a-half-point underdog, with high-scoring expectations and serious defensive concerns. Key losses include Alfred Collins (torn patellar tendon) and Sam Okuayinonu (broken foot), while Mykel Williams remains on PUP. The run defense struggled in preseason, and Romello Height is sidelined. On offense, Christian McCaffrey’s workload management looms large, with Kaelon Black and Jordan James ready to step in. Left guard remains unsettled, with no clear starter emerging and Carver Willis likely to rotate in. This opener will be a true test of depth and resilience. Listen in comfort:Get a discount on a Soli Pillow: http://solipillow.com/discount/dnn. Advertise on DNN:[email protected] This is an automated, high-level news summary based on public reporting.Report issues to [email protected]. View sources & latest updates:https://sources.thednn.ai/de07808ffea7158c