EPISODE · Oct 13, 2025 · 16 MIN
Nobel Prize in Physiology or Medicine 2025: Peripheral Immune Tolerance
from The Deep Dive Lab: Unraveling Materials Science · host Son Hoang
🔬 Scientists Mary E. Brunkow, Fred Ramsdell, and Shimon Sakaguchi were awarded the 2025 Nobel Prize in Physiology or Medicine for their groundbreaking discoveries in peripheral immune tolerance — the body’s system for preventing the immune system from attacking itself. They identified Regulatory T cells (Tregs), the “security guards” of immunity, and the FOXP3 gene, the master regulator controlling their development and function.🧬 These discoveries have revolutionized our understanding of immunity and opened new doors for treating autoimmune diseases like type 1 diabetes, lupus, and multiple sclerosis. With over 200 clinical trials underway, these findings are driving the development of more precise and effective therapies.🎧 Join us as we explore the inspiring scientific journey of these laureates and the profound impact of peripheral immune tolerance on modern medicine.#Nobel2025 #PeripheralImmuneTolerance #TregCells #FOXP3 #ModernMedicine #Immunology #AutoimmuneDiseases #PrecisionTherapy #MedicalBreakthroughs #SciencePodcast #CuriousScience
What this episode covers
🔬 Scientists Mary E. Brunkow, Fred Ramsdell, and Shimon Sakaguchi were awarded the 2025 Nobel Prize in Physiology or Medicine for their groundbreaking discoveries in peripheral immune tolerance — the body’s system for preventing the immune system from attacking itself. They identified Regulatory T cells (Tregs), the “security guards” of immunity, and the FOXP3 gene, the master regulator controlling their development and function.🧬 These discoveries have revolutionized our understanding of immunity and opened new doors for treating autoimmune diseases like type 1 diabetes, lupus, and multiple sclerosis. With over 200 clinical trials underway, these findings are driving the development of more precise and effective therapies.🎧 Join us as we explore the inspiring scientific journey of these laureates and the profound impact of peripheral immune tolerance on modern medicine.#Nobel2025 #PeripheralImmuneTolerance #TregCells #FOXP3 #ModernMedicine #Immunology #AutoimmuneDiseases #PrecisionTherapy #MedicalBreakthroughs #SciencePodcast #CuriousScience
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Nobel Prize in Physiology or Medicine 2025: Peripheral Immune Tolerance
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