Norepinephrine versus epinephrine after cardiac arrest: A systematic review and meta-analysis

Restarting the heart is only half the fight—what comes next could make or break recovery. In this episode, we dive into the high-stakes world of post-resuscitation shock and a game-changing debate: epinephrine or norepinephrine? New data from over 3,400 patients suggests norepi might dramatically cut the risk of a second cardiac arrest—by 63%! That’s huge. But does it impact survival? Brain function? Tune in as we unpack the numbers, the controversy, and what it all means for your resus playbook. Want more details? Check out the full study "Norepinephrine versus epinephrine after cardiac arrest: A systematic review and meta-analysis" by Caitlin A. Williams et al. in the American Journal of Emergency Medicine.