Novartis pelacarsen lowered Lp(a) levels in 8,323 patients—but didn't reduce cardiovascular events episode artwork

EPISODE · Sep 7, 2026 · 9 MIN

Novartis pelacarsen lowered Lp(a) levels in 8,323 patients—but didn't reduce cardiovascular events

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On September 4, 2026, Novartis and its partner Ionis Pharmaceuticals announced topline results from the Lp(a)HORIZON Phase 3 cardiovascular outcomes trial (NCT04023552).

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Novartis pelacarsen lowered Lp(a) levels in 8,323 patients—but didn't reduce cardiovascular events

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