"Old and New" Islets for Type 1 Diabetes: From Transplant to Stem Cells

In this episode, we explore the evolving world of cell therapy in type 1 diabetes. Professor James Shaw (Newcastle University), Dr Timothy Kieffer (University of British Columbia & Fractal Health), and Dr Trevor Reichman (University of Toronto) join EASD to discuss the established role of islet transplants and the exciting promise of stem cell–derived islets. The conversation covers the clinical realities of pancreas and islet cell transplants, the challenges of immunosuppression, and how scalable, gene-edited stem cell therapies could shape the future of diabetes care. From early trial successes to the potential of immune-evasive cells and gene therapies for GLP-1 delivery, today's episode examines what’s possible today and what’s coming next.