Ole Miss vs Louisville Season Opener | Louisville Football News

Ole Miss Rebels host Louisville Cardinals in a high-stakes season opener at Nissan Stadium, with the Rebels favored by 6.5 points and a projected score of 34-27. Last year’s dominant 43-24 win looms large as Louisville seeks redemption after losing key QB and WRs, while Ole Miss returns its top rusher and a solid QB. With the over/under at 55.5 and both teams’ mixed ATS records, this matchup promises drama, adaptation, and a potential season-defining performance for both programs. Listen in comfort:Get a discount on a Soli Pillow: http://solipillow.com/discount/dnn. Advertise on DNN:[email protected] This is an automated, high-level news summary based on public reporting.Report issues to [email protected]. View sources & latest updates:https://sources.thednn.ai/bdbf7c7e7c5d04a3