Ole Miss vs Louisville Season Opener Preview | Louisville Football News

Ole Miss, ranked ninth, rolls into Nashville as six-and-a-half-point favorites against Louisville, ranked twenty-fourth, in a high-stakes season opener. Led by dual-threat QB Trinidad Chambliss and a potent rushing attack anchored by Kewan Lacy, the Rebels bring firepower and a recent win over Louisville in 2021. Their revamped defense, featuring NFL-bound linebacker Suntarine Perkins and versatile secondary additions, poses a major test for Louisville’s offensive line. Meanwhile, the Cardinals, aiming for their fourth straight opening-night win under coach Jeff Brohm, look to prove they belong among the nation’s elite — especially against ranked foes. Kickoff is set for 7:30 PM on ABC — don’t miss this explosive showdown that could set the tone for the entire season. Listen in comfort:Get a discount on a Soli Pillow: http://solipillow.com/discount/dnn. Advertise on DNN:[email protected] This is an automated, high-level news summary based on public reporting.Report issues to [email protected]. View sources & latest updates:https://sources.thednn.ai/fdee6bd9d4f199f9