Omega-3 Index, Brain Health & Depression: EPA vs DHA Explained with Dr. William S. Harris episode artwork

EPISODE · Apr 10, 2026 · 57 MIN

Omega-3 Index, Brain Health & Depression: EPA vs DHA Explained with Dr. William S. Harris

from Power Up Recovery with Nutrition Podcast · host Christina Veselak

In this episode of Power Up Recovery with Nutrition, Christina Veselak sits down with Dr. Bill Harris, a leading expert in nutritional biochemistry and founder of the Omega-3 Index, to explore how omega-3 fatty acids impact brain health, mental health, and long-term recovery. Dr. Harris explains the science behind EPA and DHA, the importance of measuring omega-3 levels through the Omega-3 Index, and why this simple blood test can be a powerful predictor of health outcomes including depression, inflammation, heart disease, and even suicide risk. They dive into: • What the Omega-3 Index is and why it matters • The difference between EPA and DHA for brain function • Omega-3 deficiency and its link to mental health challenges • Optimal omega-3 intake for maintenance vs therapeutic use • Why the omega-6 to omega-3 ratio may be misleading • The role of inflammation in depression and recovery • Real-world cases of high-dose omega-3s in brain injury recovery Meet Our Guest William Harris holds a PhD in Nutritional Biochemistry from the University of Minnesota. Since 1980, his research has focused on omega-3 fatty acids. He has been the principal investigator on 8 omega-3 related NIH grants and has over 360 omega-3-related publications. In 2004, he developed the "Omega-3 Index", a blood test to assess EPA+DHA status that can be performed on dried blood spots. In 2008 he founded OmegaQuant Analytics, LLC in Sioux Falls, SD to offer the test to researchers, healthcare providers and consumers. He has been elected a Fellow of the American Heart Association, the National Lipid Association, and the American Society of Nutrition. He is currently a Professor in the Department of Medicine at the Sanford School of Medicine, University of South Dakota; President of OmegaQuant Analytics, and the founder of the Fatty Acid Research Institute (2020). His scientific impact was ranked among the top 2% in a recent survey of scientists worldwide. To Connect: Facebook: @Omega3Index Instagram: @OmegaQuant YouTube: @OmegaQuantLab Omegaquant.com (OmegaQuant) Fareinst.org (Fatty Acid Research Institute)   5 Practical Takeaways 1. Test your Omega-3 levels Use the Omega-3 Index to know where you actually stand. 2. Aim for at least 8% This is the target range linked to better brain and overall health. 3. Most people need more Omega-3s A daily intake of 1,500–2,000 mg EPA + DHA is a good starting point. 4. EPA + DHA both matter EPA supports mood and inflammation, while DHA supports brain structure. 5. Consistency is key Long-term intake matters more than occasional supplementation.   Discover More Unlock a world of resources at https://aminoacidtherapy.com/ where you'll find expert insights, transformative training, and actionable tools to support your recovery journey. Whether you're looking for professional courses like our Level 1 Core Training Learn more at https://feedtherecoveringbrain.com  Support Our Mission Check out our nonprofit initiative, Eating Protein Saves Lives, at https://eatingproteinsaveslives.org/  Learn how we're improving lives and communities through better nutrition, the science of amino acid therapy, and our simple yet powerful message: Eat protein every 4 hours. Also, if you're just starting out or want a solid foundation, check out Eat: A Guide to Radiant Recovery Using Food and Amino Acids to Repair the Addicted Brain and Reduce Cravings by Christina Veselak. It's a clear, powerful intro to the core concepts. Grab your copy here: https://www.eatforrecovery.com/ Disclaimer: This podcast is for educational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. The information shared is meant to inform and empower listeners but should not replace professional medical advice. Always consult with a qualified healthcare provider for personalized care and treatment. Music by: Bensound License code: GFZAESIUP3ZUNGXM Like this episode? Subscribe, rate, and share it with a friend or colleague who needs this information. Let's make nutrition part of the conversation for lasting recovery.

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Omega-3 Index, Brain Health & Depression: EPA vs DHA Explained with Dr. William S. Harris

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This episode was published on April 10, 2026.

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In this episode of Power Up Recovery with Nutrition, Christina Veselak sits down with Dr. Bill Harris, a leading expert in nutritional biochemistry and founder of the Omega-3 Index, to explore how omega-3 fatty acids impact brain health, mental...

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