Onc Now: Episode 28: Challenges and Hope in Kidney Cancer Research

from EMJ Podcast: Insights For Healthcare Professionals · host EMJ

In this episode, Jonathan Sackier speaks with Brian Rini, Chief of Clinical Trials at Vanderbilt-Ingram Cancer Center, Nashville, Tennessee, USA, and an internationally known leader in genitourinary oncology. The discussion explores the evolution of kidney cancer treatment, highlighting breakthroughs in immunotherapy, targeted therapy, and precision oncology. Rini shares insights from landmark clinical trials, his passion for translational research, and the challenges of broadening trial access. He also reflects on the future of the field, including the role of artificial intelligence, biomarker-driven strategies, and his hopes for advancing patient outcomes worldwide. Timestamps:   00:00 – Introduction 01:10 – Key insights into kidney cancer 03:50 – Brian's career journey 07:40 – One piece of career advice 10:40 – Diagnosis of kidney cancer 12:04 – Treatment landscape for kidney cancer 17:00 – Landmark trials in renal cell carcinoma 19:18 – Precision-based approach in trial design and selection 23:40 – Translational research 26:35 – Clinical trial recruitment 30:25 – Diversity in kidney cancer research 32:27 – ESMO 2025 highlights 35:00 – Potential of AI in trial design and recruitment 36:43 – Uncovered areas for research 38:12 – Brian's three wishes for healthcare

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This episode is 40 minutes long.

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This episode was published on November 5, 2025.

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