OpenAI's latest "bizarre" mega-deal, datacenters in space, previewing Tesla's big announcement and more | E2189 episode artwork

EPISODE · Oct 7, 2025 · 1H 16M

OpenAI's latest "bizarre" mega-deal, datacenters in space, previewing Tesla's big announcement and more | E2189

from This Week in Startups

Today's show: *How many weirdly circular mega-deals is OpenAI going to sign this year? On a new TWiST, Jason and Alex consider OpenAI's latest agreement with AMD, how the biggest American companies keep trading cash and chips back and forth, and whether or not the entire AI economy might be a house of cards. PLUS what kind of fan/leafblower tech is Tesla working on… what can Jevons Paradox tell us about the AI landscape… how easy is it to master games in the YC Arena… and WHY has NASA never built a base on the moon? We're asking the TOUGH QUESTIONS so you don't have to, only on the #1 tech podcast, "This Week in Startups." Timestamps: (0:00) Jason and Alex open the show discussing hunting and traditional Texas meat exchanges (2:16) ANOTHER weirdly circular OpenAI mega-deal? How many mega-deals can one company MAKE? (3:50) Are all these "bizarre" OpenAI deals creating a house of cards? (10:00) Stripe Startups - Stripe Startups offers early-stage, venture-backed startups access to Stripe fee credits and more. Apply today on stripe.com/startups. (20:00) Oracle - Try OCI and save up to 50% on your cloud bill at https://oracle.com/twist⁠⁠⁠ (21:14) Is the Tesla Roadster 2 coming soon? Or maybe a leaf blower?! (22:00) Datacenters in space! Is it getting crowded up there? (26:22) Why no moon base yet? Jason demands a moon base. (27:00) We're playing games in the YC Arena… Can Jason guess which pitches got accepted? (30:00) Coda - Empower your startup with Coda's Team plan for free—get 6 months at https://www.Coda.io/twist (32:00) How Jason picks companies to invest in, based on a few signals and metrics (04500) We found out what Figure's bots are actually doing for BMW (53:00) Sharpies figured out how to make their pens here in the US… who's next?! (57:00) Could ChatGPT really replace Deloitte consultants? Considering the latest controversy… (01:03:29) It's another Gamma Pitch: Welcome Ryan Yannelli of NextVisit AI, which helps therapists take notes Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.com Check out the TWIST500: https://www.twist500.com Subscribe to This Week in Startups on Apple: https://rb.gy/v19fcp Follow Lon: X: https://x.com/lons Follow Alex: X: https://x.com/alex LinkedIn: ⁠https://www.linkedin.com/in/alexwilhelm Follow Jason: X: https://twitter.com/Jason LinkedIn: https://www.linkedin.com/in/jasoncalacanis Thank you to our partners: Stripe Startups - Stripe Startups offers early-stage, venture-backed startups access to Stripe fee credits and more. Apply today on stripe.com/startups. Oracle - Try OCI and save up to 50% on your cloud bill at https://oracle.com/twist⁠⁠⁠ Coda - Empower your startup with Coda's Team plan for free—get 6 months at https://www.Coda.io/twist Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland Check out Jason's suite of newsletters: https://substack.com/@calacanis Follow TWiST: Twitter: https://twitter.com/TWiStartups YouTube: https://www.youtube.com/thisweekin Instagram: https://www.instagram.com/thisweekinstartups TikTok: https://www.tiktok.com/@thisweekinstartups Substack: https://twistartups.substack.com Subscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916

Episode metadata supplied by the publisher feed · Published Oct 7, 2025

Embed this episode

NOW PLAYING

OpenAI's latest "bizarre" mega-deal, datacenters in space, previewing Tesla's big announcement and more | E2189

0:00 1:16:27

No transcript for this episode yet

We transcribe on demand. Request one and we'll notify you when it's ready — usually under 10 minutes.

No similar episodes found.

No similar podcasts found.

Frequently Asked Questions

How long is this episode of This Week in Startups?

This episode is 1 hour and 16 minutes long.

When was this This Week in Startups episode published?

This episode was published on October 7, 2025.

Can I download this This Week in Startups episode?

Yes. Use the download control on the episode player to save the publisher-provided media file.
URL copied to clipboard!