Ophira Eisenberg on Stand Up and Storytelling!

Ophira Eisenberg is a standup comedian, writer, and host of the award-winning comedy podcast Parenting Is a Joke. She also regularly hosts and tours with the Peabody Awarding winning radio show and podcast, The Moth Radio Hour, and podcast. She also hosted NPR’s Ask Me Another for 9 years where she interviewed and played silly games with hundreds of celebrities including Sir Patrick Stewart, Rosie Perez, Yo-Yo Ma, Roxanne Gay, Nick Kroll, Chelsea Handler, and others. She’s appeared multiple times on CBS’s The Late Late Show, Sherri! with Sherri Sheppard, Comedy Central, HBO, The New York Festival, and is regular on The Moth Radio Hour. Her stories are included in three of The Moth’s best-selling collections. Her memoir, Screw Everyone: Sleeping My Way to Monogamy was optioned for a TV series, and her recent comedy special Plant Based Jokes is streaming on YouTube. She is a regular at The Comedy Cellar and other New York clubs, and her solo show Leaving A Mark: A Comedy About Scars made it’s Off-Broadway review to rave reviews and won the Women in the Arts & Media Award for Solo Show Scripts. She will be recording her new 1-hour comedy special at The Comedy Cellar in NY on Sunday Nov 9th, 2025 Such a fun chat with the very funny Ophira! We talk life, love, family, stand up, storytelling, growing up in Canada, living in NYC and, as two highly inquisitive Jews, we explore some of the burning questions about Brooklyn's Hatzalah ambulance service! Got somethin' to say?! Email us at [email protected] Leave us a message: 845-307-7446 Twitter: @AndyOstroy Produced by Andy Ostroy, Matty Rosenberg, and Jennifer Hammoud @ Radio Free Rhiniecliff Design by Cricket Lengyel