Opthal: Anterior Uveitis: Free MSRA Podcast

🎧 MSRA Podcast: Anterior Uveitis (Iritis) – Red Eye, Real RiskA focused Deep Dive into anterior uveitis, the most common uveitis type in the UK. Perfect for MSRA revision, GP triage, or acute red eye cases.🧠 What You’ll Learn✅ Definition• Inflammation of the anterior uveal tract (iris + ciliary body)• Presents with unilateral red eye, photophobia, pain• May be granulomatous (chronic/systemic) or non-granulomatous (acute/idiopathic)🧠 Mnemonic: Mutton fat KPs → think systemic disease⚠️ Key Associations• Strong links: HLA-B27 (Ankylosing Spondylitis, Psoriatic Arthritis, IBD, Reactive Arthritis)• Other: Sarcoidosis, Behçet’s, JIA, Herpes simplex, CMV, Syphilis, TB🧠 Mnemonic: A-I-I-I – Autoimmune, Infectious, Iatrogenic, Idiopathic🔬 Pathophysiology• Immune-mediated, often due to molecular mimicry• Triggers cytokine release → keratic precipitates, synechiae, flare, hypopyon🔍 Differential Diagnosis• Conjunctivitis, scleritis, acute glaucoma, herpes keratitis (no steroids!)• Other uveitis types, trauma, lens-induced inflammation🚨 Red flag: Dendritic ulcer on slit lamp = avoid steroids!📊 Epidemiology• Most common uveitis in the UK (25–50/100,000/year)• Peaks age 20–50, slight male predominance (HLA-B27)• JIA-related uveitis may be asymptomatic – screen regularly👁️ Clinical Features• Unilateral red eye, photophobia, blurred vision, lacrimation• Miotic, irregular pupil, ciliary flush, hypopyon, keratic precipitates🧠 Mnemonic: RIPP – Red eye, Irregular pupil, Photophobia, Pain🧪 Diagnosis & Investigations• Slit lamp: cells + flare in anterior chamber• IOP may be low or high• OCT: for macular oedema• Investigate if recurrent, bilateral, granulomatous, or systemic symptoms• Bloods: FBC, ESR, ACE, HLA-B27, ANA, RF, Syphilis, TB• Imaging: CXR (sarcoidosis/TB)• Infectious screen: HSV, CMV, VZV, toxoplasmosis, Lyme, HIV💊 Management• Urgent ophthalmology referral within 24 hours• Cycloplegic drops (e.g. atropine) – relieve pain, prevent synechiae• Topical corticosteroids (e.g. prednisolone) – reduce inflammation❌ Do not start steroids in primary care unless advised• If infectious: add antivirals/antibiotics• Systemic immunosuppressants for chronic/refractory cases• Monitor for glaucoma, macular oedema, cataracts with OCT + exams📉 Prognosis• Good with prompt treatment• Risk of relapse, esp. in HLA-B27• Chronic cases = higher risk of complications🚨 Complications• Glaucoma, cataracts, macular oedema, posterior synechiae• Long-term: vision loss, optic nerve damage, retinal detachment, neovascularisation📚 MSRA Resources📝 Revision Notes: https://www.passthemsra.com/topic/anterior-uveitis-revision-notes/🧠 Flashcards: https://www.passthemsra.com/topic/anterior-uveitis-iritis-flashcards/📖 Accordion Q&A: https://www.passthemsra.com/topic/anterior-uveitis-accordion-qa-notes/🎯 Rapid Quiz: https://www.passthemsra.com/topic/anterior-uveitis-rapid-quiz/🧪 Full Quiz: https://www.passthemsra.com/quizzes/anterior-uveitis/🌐 Free + Premium Resources: https://www.passthemsra.com | https://www.freemsra.com#MSRA #AnteriorUveitis #RedEye #Iritis #MSRARevision #PassTheMSRA #FreeMSRA #MSRAFlashcards #Ophthalmology #MSRApodcast #HLA_B27 #SlitLamp #VisionLoss #UKGuidelines #NICECKS #MedicalRevision