Optimising GLP-1 Use: Indications, Titration, and Monitoring

In this episode of The Good GP, Dr Sean Stevens speaks with Dr Terri-Lynne South, GP and medical director of Lifestyle Metabolic, for a focused discussion on the practicalities of prescribing GLP-1 medications. Dr Terri-Lynne shares her experience with increasing GP interest in GLP-1s, outlining both established and new indications such as type 2 diabetes, obesity, cardiovascular disease prevention, metabolic-associated steatotic liver disease (MASLD), chronic kidney disease, and obstructive sleep apnea.Dr Terri-Lynne provides clear, evidence-based guidance on dose titration, emphasising the importance of starting low and progressing gradually to minimise side effects, with schedules tailored to individual patient response. She recommended baseline and follow-up monitoring, including the use of the Bristol stool chart for baseline gastrointestinal assessment.Examining physiological effects and timelines following the discontinuation of GLP-1 therapy, with typical patterns of weight regain and metabolic reversal.Finally, highlighting the evolving role of GLP-1s as disease-modifying agents and flags upcoming advances such as dual and triple agonists and new oral medications. Dr Terri-Lynne concludes by advising GPs to set realistic patient expectations and understand the long-term management necessities of chronic disease.The Good GP Podcast is a proud member of the Talking HealthTech Podcast Network - the premier audio destination for cutting-edge insights and thought leadership in healthcare delivery, innovation, digital health, healthcare ICT, and commercialisation. Learn more at www.talkinghealthtech.com/podcast/networkIf you have any questions or would like to contact The Good GP, send an email to [email protected]. Visit www.thegoodgp.com.au for previous episodes and more information. You can also find us on our Instagram page: @thegoodgppodcast. Follow us for more updates!Mentioned in this episode:Build the Career and Lifestyle You’ve Been Looking For, in the Vines.Tired of traffic, long commutes, and feeling stuck in the grind? The Mudgee Region is calling. The Doctors 4 Mudgee Region initiative is working to attract and support GPs and registrars looking to build rewarding, sustainable careers in one of NSW’s most sought after regional destinations, just 3 hours from Sydney. With financial incentives of up to $45,000 for fellowed doctors and lifestyle concierge support for all relocating practitioners, there’s never been a better time to make the move. Learn more at www.doctors4mudgee.com.auDoctors 4 Mudgee Region